Magic truffles and MAO inhibitors

In the meantime, it has become apparent that combining MAO inhibitors and psilocybin barely increases the risk of serotonin syndrome. In fact, with Psilohuasca and Psiloflora An MAOi is intentionally added to truffles, psilocybin, or magic mushrooms to enhance and prolong the effects. This is typically done with reversible MAO-A inhibitors such as harmaline and harmine, derived from plants like Banisteriopsis caapi or Passiflora. This form of MAO inhibition is temporary and relatively safe when no other serotonergic substances are combined, such as SSRIs or MDMA.

At psilohuascaWith -like preparations, psilocybin can remain active in the body longer, resulting in more intense visual and introspective effects. However, it is important that users screen for medication use and physical or mental sensitivities beforehand.

If you are using MAOIs as medication, it is helpful to check for each medication whether tapering off is necessary or recommended.