If you use alprazolam, for example, before the psychedelic session, how many days should you refrain from using it to avoid its influence during therapy?
Alprazolam EG is a brand name of alprazolam, a medicine belonging to the benzodiazepines. It is primarily prescribed for anxiety disorders, panic disorders, and sometimes for short-term severe tension complaints.
Alprazolam enhances the action of the neurotransmitter GABA (gamma-aminobutyric acid) in the brain. As a result, signal transmission in the brain is inhibited, which leads to a anxiety-reducing, calming and muscle-relaxing effect.
The dosage varies per person and indication. Doctors usually start with a low dose which is slowly increased if necessary. Alprazolam works relatively soon after ingestion and the operation holds on average 6 to 12 hours On.
The half-life of alprazolam lies between the 11 and 16 hours (sometimes shorter or longer depending on age, liver function, and individual differences).
According to the 5× half-life rule has a substance almost completely disappeared from the body after approximately:
In the elderly and people with impaired liver function, this time may be longer.
Common side effects are:
Prolonged use can lead to tolerance, dependence and withdrawal symptoms at stopping.
Because alprazolam can strongly suppress psychedelic effects (due to the inhibitory effect on brain activity), it is important that the drug has disappeared from the body before a session takes place.
Since the elimination approximately 2.5 to 3.5 days lasts (in healthy adults), it is often recommended to at least 3 days do not use alprazolam before a psychedelic session. For extra certainty and to prevent any residual effects from remaining, a waiting time of 4 to 5 days be better.