[Solved] Can psilocybin be taken with sertraline?

Yes, recent research suggests that combining psilocybin (the active ingredient in magic mushrooms/truffles) with sertraline (an SSRI medication) is generally safe. Although sertraline may slightly reduce the effects of psilocybin, it appears that the therapeutic effects of psilocybin are still present, albeit possibly less intense.

It is always best to discuss plans to start using psilocybin with the doctor who prescribed Sertraline, as individual circumstances can vary. The doctor can provide advice on tapering off the medication if necessary. Never stop taking medication abruptly without consulting a doctor.

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