[Solved] Psychedelic therapy for depression

Dozens of extensive reviews on the Triptherapie forum show that psychedelic therapy (with psilocybin, truffles, or MDMA) has a positive, sometimes life-changing, impact on depression for many people. The experiences vary, but there are some common insights:

1. Breakthrough after years of therapy: Many people who used conventional therapy or antidepressants for years report that psychedelic sessions finally lead to profound insights and actual behavioral changes. Letting go of control, embracing emotions, and breaking limiting patterns are particularly mentioned in this context.

2. Restoration of hope, energy, and zest for life: After sessions, participants often experience a renewed sense of lightness, purpose, and positivity. Phrases such as “mentally 10 kilos lighter again,” “new perspective,” “structurally less gloomy,” “strength to move forward,” and “life feels possible again” are frequently heard.

3. Personal guidance is essential: The role of the tripsitter/therapist is consistently emphasized. Expert, empathetic guidance proves to be of great importance for a safe and fruitful experience.

4. Medical effect and integration: Some report a structural reduction in depressive symptoms, a decrease in medication, and increased motivation to make healthy choices. Integration (translating insights into daily behavior) is important in this regard.

5. Not a miracle cure for everyone: Although the majority of reviews are positive, psychedelic therapy remains a personalized approach and not a universal solution. For some, the impact is less significant or more sessions are needed.

Overview of reviews of therapeutic psychedelics sessions for depression:

Trip therapy for depression and OCD with Ronald
“After nearly three years of severe depression and OCD, during which therapies brought little improvement, I took the plunge and tried a psilocybin session. The preparation with Janneke provided a sense of calm, as the anxiety was intense. During the session, Ronald helped me embrace the fear. Not the horror trip I dreaded, but rather an intense experience of white light, physical lightness, and the realization that my core was intact. A sense of peace and hope returned after being stuck for years. The session helped to distance myself from problems, break through the 'depressed' label, and integrate constructive insights.‘
Read full: Trip therapy for depression and OCD with Ronald

Tripping for depression – guidance by Marcel
“Two truffle sessions guided by Marcel gave me insights that other forms of therapy couldn't reach. Marcel knows an incredible amount and truly listens. He helps consider the physical causes of fatigue and depression. His tips and open style made it a special trip.”
Read full: Tripping for depression

After years of depression, I am starting to regain hope! – session with Reineke
“After persistent, recurring depression, I attended an individual psilocybin session with Reineke Brandt. Everything went smoothly and pleasantly, from preparation to aftercare. The next day I still felt floaty and mentally 10 kilos lighter – no hangover, but a mild headache. The psilocybin brought about a significant improvement; I am much less gloomy and have structurally more hope and zest for life.”
Read full: After years of depression, I am starting to get hope again!

Healing MDMA session Ronald for depression
“After ten years of therapy, I did not get to the essence of my suffering. An MDMA session finally brought a breakthrough: letting go of control was intense, and deeply hidden emotions and patterns surfaced. Ronald taught me to look at myself with compassion. The recovery and insights finally give me the feeling that my life can begin again.”
Read full: Healing MDMA session Ronald for depression

Truffle session for depression and anxiety
“A medium dose of truffles under guidance made me feel lighter. It was profound and emotional; processing took time. Marcel is patient, skilled, and committed. The trip yielded a great deal of personal peace and insights.”
Read full: Truffle session for depression and anxiety

Truffle trip level 3-4 – with Marcel
“Home truffle therapy with Marcel led to beautiful visualizations and a completely different perspective on my surroundings. My depressive symptoms have significantly decreased. Now I exercise more, eat healthier, meditate, and am much more active and positive.”
Read in full: Truffle trip level 3-4

Psychedelic session for my mother of 70+ with OCD, childhood trauma, and depression
“After twenty years of low energy, depression, and deep periods of gloom, one session at Marcel and Janneke brought about a complete turnaround. She now rates her life a solid 8 and can let go of rules in her daily life, something that seemed impossible for years.”
Read full: Psychedelic session for my mother of 70+ with OCD, childhood trauma, and depression

MDMA trip 1 & 2 – with Sascha
“My MDMA sessions with Sascha provided deep insights. Scientific doubt was combined with the experience of inexplicable feelings. Letting go of control and rational thinking resulted, after blockages and panic, in immense peace and a deepening of life.”
Read full: MDMA trip 1 & 2

Great experience with MDMA therapy – with Ronald
“After more than 10 years of psychologists and ineffective treatments, I felt reborn after MDMA therapy. I am happier, see life in a more positive light, and those around me notice enormous positive changes.”
Read full: Amazing experience with MDMA therapy

Three years after my truffle session – with Marcel
“From youth, I struggled with anxiety disorders and depression, an arsenal of medication, and avoidance behavior. Three years after the truffle therapy, I have lost 56 kilos, have social contacts, work, and hope again. The insights are not airy-fairy, but practical and life-changing.”
Read full: Three years after my truffle session

In conclusion: For many people with depression, psychedelic therapy appears to be a powerful complementary tool alongside conventional treatments, especially when there is frustration within the conventional system or when seeking depth, emotional breakthroughs, and new inspiration. The insights from the forum are personal and varied, but the majority are hopeful and positive. Safety, preparation, and aftercare are crucial for the success of this form of therapy.

See also:

Psychedelic therapy | All reviews

At Triptherapie, I have personally guided over 2,200 people during a trip. Many of them were also dealing with depression or depressive symptoms, and most of these clients opted for a psilocybin session (with legal truffles). My personal estimate is that for about 7 out of 10 people, a breakthrough occurs after just 1, 2, or only 3 sessions, resulting in fewer depressive symptoms or being declared in remission.

Furthermore, psilocybin works even better for depression if, in addition to the session itself, you also work on physical health, proper preparation, and integration. During the session itself, besides the standard biological effects of psilocybin, the following are often indicators of extra success: emotional release, a sense of overcoming something such as a fear, many tears, transcendence, ego death, spirituality, a challenging start followed by letting go, introspection during peak effects, confronting fears, and a general sense of satisfaction or inner peace.

The deeper the trip, the greater the effect on me. Mystical experiences and ego death were particularly important to me. I am now also more involved with spiritual halls, and that helps me even after the trip.