[Solved] Can I do mushroom trip therapy if I use Bisoprolol fumarate?

Magic mushrooms and truffles contain psilocybin, which is converted into psilocin, and this substance affects blood pressure rather than heart rate (XTC does increase blood pressure and heart rate). Blood pressure rises only slightly at the beginning of a deeper trip. Bisoprolol fumarate is a beta-blocker and actually lowers blood pressure and slows the heart rate. Because bisoprolol fumarate and psilocybin are polar opposites, the effect is not as shocking.

What I would recommend is to start a blood pressure-lowering diet at least two weeks in advance and to refrain from drinking alcohol and/or using other drugs. This means eating healthily with plenty of potassium-rich vegetables and less sodium (salt). A healthy lifestyle should already ensure that you need less Bisoprolol fumarate. It would be great if you measured your blood pressure occasionally while you adjust your diet.

Also discuss your intention to adjust your diet with your doctor and review together if the medication can be reduced. It would be wonderful if this were the start of a healthier life.

The use of Bisoprolol fumarate is in most cases no absolute contraindication for undergoing mushroom or truffle therapy. Bisoprolol fumarate is a beta-blocker that is primarily prescribed to treat high blood pressure, heart rhythm disorders, and certain heart conditions. If you are considering taking a mushroom trip (with psilocybin) while using Bisoprolol fumarate, there are some important points to keep in mind:

Key points of attention:

1: Interaction with psilocybin:

• There are no direct known serious interactions between beta-blockers (such as Bisoprolol) and psilocybin.
• Psilocybin can cause temporary changes in heart rate and blood pressure. In beta-blocker users, the effect on heart rate may be less noticeable because beta-blockers slow the heart rate.

2: Heart rate and blood pressure:

• Psilocybin can temporarily increase or decrease blood pressure and heart rate. If you take medication that regulates heart rate and blood pressure (such as Bisoprolol), it may become more difficult to clearly feel changes.
• Although beta-blockers generally offer protection against rapid heart rate and severe blood pressure fluctuations, a small risk remains of unwanted side effects, such as dizziness, fainting, or fatigue during a mushroom trip.
• Sometimes, psilocybin use actually results in lower blood pressure. Be careful when combining with beta-blockers so that you are not surprised by dangerously low blood pressure after the session.

3: Psychological effects:

• Bisoprolol itself sometimes causes mild fatigue or a feeling of weakness. Combined with psilocybin, this can make you feel less energetic or more emotional during your trip.

4: Advice and safety:

• Always consult your treating physician first, especially if you are taking beta-blockers or other heart medication.
• Start with a low dose of psilocybin if permission has been obtained from your doctor.
• Ensure a safe, quiet environment and the presence of an experienced tripsitter or therapist during the session.
• Have electrolytes on hand to regulate blood pressure.

Conclusion:

Although no direct serious interactions are known, caution is advised due to possible effects on heart rate and blood pressure. Therefore, always consult your doctor before planning a mushroom trip in combination with Bisoprolol fumarate.