26 February 2024 16:26
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Psilocybin + MDMA = Hippylip
Yes, psilocybin and MDMA can be combined, and this is called the hippie flip. Whether combining these two substances is wise is another question. When combining drugs, interactions and synergy must be taken into account. When dosing the hippie flip, the synergistic effect must be considered to prevent overdose. Regarding physical safety, in addition to a stronger effect and overdose, the risk profile is approximately the same as MDMA on its own.
View more information about these two substances and the contraindications on the following pages:
Also check out the following article about the hippie flip:
2 Answers
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29 June 2025 09:01
Yes, you can combine psilocybin with MDMA in what is called a hippie flip. This combination is being used increasingly often in Triptherapie, especially for people who do want a deep psychedelic experience but struggle with anxiety or a strong need for control. MDMA has an anxiety-reducing and bonding effect, whereby the psilocybin trip feels safer and more accessible.
During a hippie flip, MDMA creates feelings of safety, empathy, and connection. This makes it easier to surrender to the visual, emotional, and spiritual effects of psilocybin. This combination can lead to deeper insights, increased self-compassion, gratitude, and — notably, according to a 2023 scientific study — even a lower risk of a bad trip compared to psilocybin alone, provided the dosages are properly adjusted.
With Triptherapie, dosages are determined personally based on your sensitivity, experience, and goals. The MDMA dosage typically ranges between 50 and 150 mg, and psilocybin between 15 and 45 mg. Timing is also important: MDMA is often taken first, followed by psilocybin after a certain time, so that the peaks of both substances align well.
The combination affects the serotonergic systems in the brain, so it is essential that you have no contraindications such as SSRI use or heart problems. Via the intake for trip therapy is this checked in advance.
Many people choose the hippie flip as an alternative to classic MDMA or psilocybin sessions, precisely because it combines the benefits of both agents.
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5 February 2026 20:28
Yes, this was once one of my best tripping experiences ever. The MDMA removes all negative emotion from a trip so that you can trip with complete surrender. Even the day after, I felt great and had almost no comedown, because I needed MDMA due to the Minddr combo.