Can you mix LSD and oxycodone?

@oxymoron 

Posted by: @oxymoron

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Can you mix LSD and oxycodone?

There are no extensive studies that specifically examine the interaction between LSD and oxycodone studies. This means that little is known about the direct effects of this combination. However, it is important to understand that the use of psychedelics such as LSD in combination with opioids such as oxycodone can be potentially risky.

One of the main concerns when combining these substances is the risk of respiratory depression, which can occur with the use of opioids. LSD can alter perception and consciousness, which can lead to impaired self-assessment and increase the risk of oxycodone overdose. Furthermore, the effects of LSD, such as anxiety or paranoia, can be exacerbated by the sedative effects of oxycodone.

There are also reports of the serotonin syndrome, a potentially life-threatening condition that can occur when combining substances that increase serotonin levels in the brain. Although oxycodone does not act directly on the serotonergic system, the effects of LSD in combination with other substances can be unpredictable.

For the time being, combining oxycodone and LSD is therefore advised against due to a lack of clarity. Some people choose not to use oxycodone the day before an LSD trip. In theory, refraining from taking oxycodone for 20 hours before using LSD is sufficient to minimize or prevent potential interactions and side effects.