7 December 2024 11:13
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Why do people take trips with frog venom?
10 December 2024 21:14
Why do people take trips with frog venom?
A trip with frog venom, or kambo session, is often undertaken by individuals who cannot be effectively helped by Western medicine. Ingesting frog venom or kambo causes the immune system to overreact. This can lead to intense physical reactions such as vomiting, sweating, and other symptoms that are often experienced as a kind of 'cleansing.' The idea behind these sessions is that, through these intense reactions, the body would be able not only to process the effects of the frog venom but also to address other underlying health issues that might otherwise remain undetected.
However, scientific studies cannot demonstrate that kambo works significantly better than a placebo. This may mean that the studies are not well designed or that the administration of frog venom provides no benefit to many people. At Triptherapie, we choose to use only psychedelics that have been scientifically proven to have therapeutic potential. It is important to acknowledge that although some people believe kambo has helped them, the risks and potential side effects of using frog venom can be significant, especially for people who are already ill. Therefore, it is crucial to be well-informed and to choose treatments that are supported by solid scientific evidence.
See also:
LSD therapy | MDMA therapy | Truffle therapy | Psilocybin therapy | Psychedelic therapy
2 Answers
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4 November 2025 12:20
Kambo is indeed something that enjoys a lot of interest in certain wellness and alternative medicine circles. What you should know is that kambo likely derives its appeal from a combination of physiological and psychological factors, rather than from direct therapeutic effects.
Kambo is obtained from the secretion of frogs of the genus Phyllomedusa. This secretion indeed contains bioactive peptides—including phyllocaerulein, phyllokinin, sauvagine, and also natural opioid-like peptides such as dermorphin. These substances have demonstrable biological activity: they activate certain receptors in the body and can have analgesic and anti-inflammatory effects.
However, the severe purging effect that people experience can largely be explained by the fact that these peptides directly stimulate the gastrointestinal tract. The intense physical reactions—vomiting, diarrhea, blurred vision, palpitations—are actually symptoms of the body defending itself against these substances. Some people interpret these reactions as 'healing' or 'cleansing,' but this is primarily a result of the substances being toxic, not of any specific therapeutic effect.
Regarding scientific evidence: there is indeed little research demonstrating that kambo specifically helps with certain conditions better than a placebo. This does not mean that it can never be effective, but rather that we currently have insufficient evidence. Nevertheless, kambo does contain substances that are theoretically interesting for further research.
The risk is that kambo can cause serious medical complications, especially in people with heart problems, high blood pressure, or poor health. The intense physiological stress on the body can even be fatal for some.
When opting for experimental therapeutic interventions, it is therefore wise to ask yourself: do I have scientific evidence for this, and what are the demonstrable risks? Kambo does not score very well on either point.
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6 November 2025 09:36
Frog venom (5-MeO-DMT) contains a very strong psychedelic substance. People use it for intense spiritual experiences. The effects are powerful but short, which is attractive to some.