[Solved] Microdose

Microdosing psychedelics works best with LSD or psilocybin. Other substances like MDMA are not really suitable for this. Sometimes we choose LSD because the duration of action is longer and you can use it for a longer period during the microdosing day. However, most people choose psilocybin (truffles).

Microdosing is becoming increasingly popular as a method to improve mood, creativity, and mental clarity. The most commonly used and researched psychedelics for microdosing are:

1️⃣ Psilocybin (magic mushrooms/truffles) – most popular 🍄

✅ How does it work?

• Psilocybin is converted in the body into psilocin, which activates serotonin receptors.
• It stimulates neuroplasticity and can help with depression, anxiety and focus problems.

✅ Why popular?

• Well-documented and researched.
• Naturally and legally available as truffles in the Netherlands.
• Has relatively mild side effects and a gentle effect with microdoses.

✅ Microdosing schedule
🔹 Dose: 0.1 – 0.2 grams of dried magic mushrooms or 0.5 – 2 grams of fresh truffles.
🔹 Protocol:

• Fadiman protocol (1 day on, 2 days off)
• Stamets stacking (5 days on, 2 days off, often with niacin and lion's mane mushroom)

📌 Good for: Mood, creativity, social openness, emotional balance.

2️⃣ LSD (Lysergic acid diethylamide) – powerful and clear 🎨

✅ How does it work?

• LSD binds to serotonin receptors and stimulates long-term brain network activation.
• Is often used for focus, productivity and creativity.

✅ Why popular?

• Longer duration of action (8-12 hours).
• Small amounts provide a subtle mental energy boost.

✅ Microdosing schedule
🔹 Dose: 5 – 40 µg (1/10th to 1/20th of a normal trip dose).
🔹 Protocol:

• Fadiman protocol (1 day on, 2 days off).
• Workweek protocol (4 days on, 3 days off).

📌 Good for: Concentration, productivity, creativity, mental clarity.

⚠️ NB: LSD is illegal in many countries and can sometimes insomnia or nervousness cause.

3️⃣ 1P-LSD or ALD-52 – legal LSD variants in some countries 🧪

✅ How does it work?

• These are LSD analogues which are converted into LSD in the body.
• Works almost identically, but slightly milder and shorter (6-10 hours).

📌 Good for: The same benefits as LSD, but can feel slightly more subtle.
⚠️ NB: Legal status varies by country.

4️⃣ Mescaline (San Pedro/Peyote) – rare but spiritual 🌵

✅ How does it work?

• Mescaline is a classic psychedelic alkaloid that activates serotonin receptors.
• Has a Very mild and warm effect with microdoses.

✅ Why less popular?

• More difficult to dose because the concentration varies per cactus.
• Can more physical side effects give (nausea, feeling of warmth).
• Long duration of action (10-14 hours), which makes microdosing more difficult.

📌 Good for: Spiritual introspection, emotional balance, connection with nature.

5️⃣ MDMA – NOT a suitable option for microdosing ❌

❌ Why not?

• MDMA works differently from classic psychedelics: it depletes serotonin instead of activating receptors.
• Regular use can lead to serotonin depletion and depressive feelings.
• Microdosing with MDMA has no proven benefits and is not recommended.

📌 Suitable for: Therapy sessions in full MDMA doses (such as in PTSD treatment).

Which one is best for you? 🤔

🔹 For mood, emotional balance & creativity → Psilocybin 🍄
🔹 For productivity & mental clarity → LSD or 1P-LSD 🎨