Can you go on an LSD trip whilst you’re still microdosing on truffles?
If you’re going to go on an LSD trip whilst also microdosing, you may find that, due to habituation, the LSD trip feels less intense. This is because the body can adapt to the constant presence of psychedelics, which may mean that the effects of a higher dose of LSD are less intense. This is because microdosing with truffles can increase the levels of MAO enzymes.
The increase in monoamine oxidase (MAO) enzymes therefore contributes to the development of tolerance. MAO is an enzyme responsible for the breakdown of serotonin and other neurotransmitters in the brain. When microdosing truffles, which can also have psychedelic effects due to the presence of psilocybin, the level of MAO enzymes may increase. This can lead to a faster breakdown of psychedelics, making the effects less intense. If you then take a substance similar to LSD, the effects may be reduced due to cross-tolerance.
If you want to reduce your tolerance to truffles or other psychedelics, it is advisable to avoid taking psychedelics for 1 to 2 weeks. This helps to restore the MAO enzymes in your body to normal levels, which may increase the effectiveness of LSD during a future session. It is important to observe this period of abstinence in order to maximise the desired effects of the psychedelics and prevent unwanted interactions.
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