14 January 2025 13:33
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Can benzodiazepines be taken together with psilocybin?
14 January 2025 22:16
Can benzodiazepines be taken together with psilocybin?
You must be very careful when combining psilocybin with medication. When combining it with benzodiazepines, also known as 'pams', such as Normison (temazepam), there is a chance of reduced effectiveness of the psilocybin experience. Benzodiazepines work by increasing activity on GABA receptors, which leads to an inhibitory effect on nerve cells. This can result in a less intense experience of the psychedelic effects of psilocybin.
It is sometimes recommended to taper off benzodiazepines, if possible, before you a psilocybin session undergoes. In the case of Normison, the half-life is approximately 8-10 hours, which means that it can take about 40-50 hours (approximately 2 days) before the medication no longer has an inhibitory effect on psilocybin. It is always recommended to consult a doctor first before deciding to stop using medication and not to consider this as medical advice.
2 Answers
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30 April 2025 22:33
Combining pills Combining (benzodiazepines such as diazepam, oxazepam, or lorazepam) with psilocybin is in principle not dangerous, but it is problematic from a therapeutic point of view. Benzodiazepines have a sedative effect and suppress the activity of the central nervous system. As a result, they can significantly weaken the psychedelic effects of psilocybin or even block them almost completely. This means that a psilocybin session less effective or even pointless can be if benzodiazepines are still present in the system.
The use of tranquilizers poses only a minimally slightly increased risk, but it is mainly the The therapeutic effect of psilocybin is undermined. Therefore, it is strongly recommended to stop this medication first to taper off under the supervision of a doctor or specialist before you a truffle session or psilocybin session undergoes.
In short: if you want to get the maximum therapeutic effect from a psilocybin experience, it is important not to use benzodiazepines before the session. A different time limit applies to each benzodiazepine during which you cannot use it. If you want to handle this responsibly, you can via the intake for trip therapy have the best approach for your situation assessed.
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19 June 2025 12:20
In most cases, therefore, it is better not to take a tranquilizer for a few days before a trip.